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Stigmasterol Simultaneously Induces Apoptosis and Protective Autophagy by Inhibiting Akt/mTOR Pathway in Gastric Cancer Cells

BACKGROUND: Stigmasterol (SS) has been proven to possess potential anticancer activities in several cancer cell lines, but its molecular mechanism is still unknown. Thus, we investigated whether SS has the capabilities of inducing autophagy and its molecular mechanisms in gastric cancer cells. METHO...

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Detalles Bibliográficos
Autores principales: Zhao, Huange, Zhang, Xian, Wang, Min, Lin, Yingying, Zhou, Songlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940753/
https://www.ncbi.nlm.nih.gov/pubmed/33708631
http://dx.doi.org/10.3389/fonc.2021.629008