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Current evidence and the emerging role of eltrombopag in severe aplastic anemia

Acquired aplastic anemia (AA) is characterized by a reduced stem cell reserve. Several preclinical studies have confirmed the beneficial effect of thrombopoietin (TPO) on the expansion and maintenance of hematopoietic stem cells (HSCs). Thus, TPO receptor agonists seem to be an ideal therapeutic age...

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Detalles Bibliográficos
Autores principales: Drexler, Beatrice, Passweg, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940771/
https://www.ncbi.nlm.nih.gov/pubmed/33747425
http://dx.doi.org/10.1177/2040620721998126