Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model: the first pre-clinical study for safety and efficacy in China

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly due in large part to age-dependent atrophy of retinal pigment epithelium (RPE) cells. RPE cells form a monolayer located between the choroid and the outer segments of photoreceptors, playing multifari...

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Detalles Bibliográficos
Autores principales: Zhang, Hang, Su, Bingnan, Jiao, Luyan, Xu, Ze-Hua, Zhang, Chang-Jun, Nie, Jinfu, Gao, Mei-Ling, Zhang, Ying V., Jin, Zi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940887/
https://www.ncbi.nlm.nih.gov/pubmed/33708872
http://dx.doi.org/10.21037/atm-20-4707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940887/
https://www.ncbi.nlm.nih.gov/pubmed/33708872
http://dx.doi.org/10.21037/atm-20-4707

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