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Investigating the protective effect of tanshinone IIA against chondrocyte dedifferentiation: a combined molecular biology and network pharmacology approach

BACKGROUND: Osteoarthritis (OA) is a common degenerative disease with multifactorial etiology. The dedifferentiation of chondrocytes can accelerate the progress of OA. Tanshinone IIA (TIIA) has been widely used to treat OA for many years and has proved to be effective in inhibiting chondrocyte dedif...

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Detalles Bibliográficos
Autores principales: Zhang, Yushen, Sun, Liguo, Liu, Xincheng, Zhu, Dongze, Dang, Jingyi, Xue, Yingsen, Fan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940936/
https://www.ncbi.nlm.nih.gov/pubmed/33708876
http://dx.doi.org/10.21037/atm-20-4023