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Investigating the protective effect of tanshinone IIA against chondrocyte dedifferentiation: a combined molecular biology and network pharmacology approach
BACKGROUND: Osteoarthritis (OA) is a common degenerative disease with multifactorial etiology. The dedifferentiation of chondrocytes can accelerate the progress of OA. Tanshinone IIA (TIIA) has been widely used to treat OA for many years and has proved to be effective in inhibiting chondrocyte dedif...
Autores principales: | Zhang, Yushen, Sun, Liguo, Liu, Xincheng, Zhu, Dongze, Dang, Jingyi, Xue, Yingsen, Fan, Hongbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940936/ https://www.ncbi.nlm.nih.gov/pubmed/33708876 http://dx.doi.org/10.21037/atm-20-4023 |
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