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The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA

BACKGROUND: In our recent study using [U–(13)C(3)]glycerol, a small subset of hamsters showed an unusual profile of glycerol metabolism: negligible gluconeogenesis from glycerol plus conversion of glycerol to 1,3-propanediol (1,3PDO) and 3-hydroxypropionate (3HP) which were detected in the liver and...

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Detalles Bibliográficos
Autores principales: Jin, Eunsook S., Lee, Min H., Malloy, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940983/
https://www.ncbi.nlm.nih.gov/pubmed/33733082
http://dx.doi.org/10.1016/j.metop.2021.100086