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The presence of 3-hydroxypropionate and 1,3-propanediol suggests an alternative path for conversion of glycerol to Acetyl-CoA
BACKGROUND: In our recent study using [U–(13)C(3)]glycerol, a small subset of hamsters showed an unusual profile of glycerol metabolism: negligible gluconeogenesis from glycerol plus conversion of glycerol to 1,3-propanediol (1,3PDO) and 3-hydroxypropionate (3HP) which were detected in the liver and...
Autores principales: | Jin, Eunsook S., Lee, Min H., Malloy, Craig R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940983/ https://www.ncbi.nlm.nih.gov/pubmed/33733082 http://dx.doi.org/10.1016/j.metop.2021.100086 |
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