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Deuteration enhances the anti-tumor effects and relative anti-inflammatory effects via affecting proliferation and apoptosis
Apigenin (AP) is a plant flavonoid with potential biomedical applications. To enhance the anti-tumour effect, AP was deuterated via hydrogen–deuterium exchange under hydrothermal conditions. The anti-tumor effects of deuterated AP (D-AP) were then tested on HCT116 cells and on a murine model of turp...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941159/ https://www.ncbi.nlm.nih.gov/pubmed/33732929 http://dx.doi.org/10.1016/j.heliyon.2021.e06391 |