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Deuteration enhances the anti-tumor effects and relative anti-inflammatory effects via affecting proliferation and apoptosis

Apigenin (AP) is a plant flavonoid with potential biomedical applications. To enhance the anti-tumour effect, AP was deuterated via hydrogen–deuterium exchange under hydrothermal conditions. The anti-tumor effects of deuterated AP (D-AP) were then tested on HCT116 cells and on a murine model of turp...

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Detalles Bibliográficos
Autores principales: Li, Ao, Wang, Xiaojiao, Li, Danni, Li, Xiaohong, Li, Rou, Yang, Xuejuan, Li, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941159/
https://www.ncbi.nlm.nih.gov/pubmed/33732929
http://dx.doi.org/10.1016/j.heliyon.2021.e06391