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Nestorone(®), a 19nor‐progesterone derivative boosts remyelination in an animal model of demyelination

INTRODUCTION: We previously showed that Nestorone(®) (NES), a synthetic progestin structurally related to progesterone, stimulated remyelination of the corpus callosum in a Cuprizone (CUP) mouse model of demyelination in intact females by promoting replenishment with mature oligodendrocytes (OL) (Gl...

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Detalles Bibliográficos
Autores principales: El‐Etr, Martine, Akwa, Yvette, Rame, Marion, Schumacher, Michael, Sitruk‐Ware, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941173/
https://www.ncbi.nlm.nih.gov/pubmed/33369182
http://dx.doi.org/10.1111/cns.13538