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A novel palmitic acid hydroxy stearic acid (5‐PAHSA) plays a neuroprotective role by inhibiting phosphorylation of the m‐TOR‐ULK1 pathway and regulating autophagy

AIMS: Type 2 diabetes mellitus (T2DM) can lead to brain dysfunction and a series of neurological complications. Previous research demonstrated that a novel palmitic acid (5‐PAHSA) exerts effect on glucose tolerance and chronic inflammation. Autophagy was important in diabetic‐related neurodegenerati...

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Detalles Bibliográficos
Autores principales: Wang, Jian‐tao, Yu, Zhong‐yu, Tao, Ying‐hong, Liu, Ying‐chao, Wang, Yan‐mei, Guo, Qi‐lin, Xue, Jian‐zhong, Wen, Xiao‐hong, Zhang, Qian, Xu, Xiao‐die, He, Cheng‐feng, Xue, Wen‐jiao, Guo, Jing‐chun, Zhou, Hou‐guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941174/
https://www.ncbi.nlm.nih.gov/pubmed/33459523
http://dx.doi.org/10.1111/cns.13573