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Reducing TGF‐β1 cooperated with StemRegenin 1 promoted the expansion ex vivo of cord blood CD34(+) cells by inhibiting AhR signalling
OBJECTIVE: As an inhibitor of the AhR signalling pathway, StemRegenin 1 (SR1) not only promotes the expansion of CD34(+) cells but also increases CD34(−) cell numbers. These CD34(−) cells influenced the ex vivo expansion of CD34(+) cells. In this work, the effects of periodically removing CD34(−) ce...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941221/ https://www.ncbi.nlm.nih.gov/pubmed/33522060 http://dx.doi.org/10.1111/cpr.12999 |