Nbs1‐mediated DNA damage repair pathway regulates haematopoietic stem cell development and embryonic haematopoiesis

OBJECTIVES: DNA damages pose threats to haematopoietic stem cells (HSC) maintenance and haematopoietic system homeostasis. Quiescent HSCs in adult mouse bone marrow are resistant to DNA damage, while human umbilical cord blood‐derived proliferative HSCs are prone to cell death upon ionizing radiatio...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Sun, Jie, Ju, Zhenyu, Wang, Zhao‐Qi, Li, Tangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941224/
https://www.ncbi.nlm.nih.gov/pubmed/33586242
http://dx.doi.org/10.1111/cpr.12972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941224/
https://www.ncbi.nlm.nih.gov/pubmed/33586242
http://dx.doi.org/10.1111/cpr.12972

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