Cargando…

The TSPO-specific Ligand PK11195 Protects Against LPS-Induced Cognitive Dysfunction by Inhibiting Cellular Autophagy

Perioperative neurocognitive disorders (PND) is a common postoperative neurological complication. Neuroinflammation is a major cause that leads to PND. Autophagy, an intracellular process of lysosomal degradation, plays an important role in the development and maintenance of nervous system. PK11195...

Descripción completa

Detalles Bibliográficos
Autores principales: Lan, Nannan, Liu, Yongxin, Juan, Zhaodong, Zhang, Rui, Ma, Baoyu, Xie, Keliang, Sun, Lina, Feng, Hao, Sun, Meng, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941270/
https://www.ncbi.nlm.nih.gov/pubmed/33708121
http://dx.doi.org/10.3389/fphar.2020.615543