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The TSPO-specific Ligand PK11195 Protects Against LPS-Induced Cognitive Dysfunction by Inhibiting Cellular Autophagy
Perioperative neurocognitive disorders (PND) is a common postoperative neurological complication. Neuroinflammation is a major cause that leads to PND. Autophagy, an intracellular process of lysosomal degradation, plays an important role in the development and maintenance of nervous system. PK11195...
Autores principales: | Lan, Nannan, Liu, Yongxin, Juan, Zhaodong, Zhang, Rui, Ma, Baoyu, Xie, Keliang, Sun, Lina, Feng, Hao, Sun, Meng, Liu, Jianfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941270/ https://www.ncbi.nlm.nih.gov/pubmed/33708121 http://dx.doi.org/10.3389/fphar.2020.615543 |
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