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The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): Revised characterisation of cytogenetic features

BACKGROUND: Haematological malignancies harbouring rearrangements of the KMT2A gene represent a unique subtype of leukaemia, with biphenotypic clinical manifestations, a rapid and aggressive onset, and a generally poor prognosis. Chromosomal translocations involving KMT2A often cause the formation o...

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Detalles Bibliográficos
Autores principales: Ragusa, Denise, Makarov, Evgeny M., Britten, Oliver, Moralli, Daniela, Green, Catherine M., Tosi, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941496/
https://www.ncbi.nlm.nih.gov/pubmed/32721124
http://dx.doi.org/10.1002/cnr2.1207