Oncolytic effect of Midkine promoter–based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T891

BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinomas (HNSCCs). Midkine expression is restricted in adult tissues but is increased in several malignant tumors, including HNSCCs. AIM: Here, we evaluated the antitumor effect of Midkine promoter–...

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Detalles Bibliográficos
Autores principales: Uehara, Natsumi, Otsuki, Naoki, Kubo, Mie, Kitamoto, Junko, Kojima, Yasutaka, Teshima, Masanori, Shinomiya, Hirotaka, Shirakawa, Toshiro, Nibu, Ken‐ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941548/
https://www.ncbi.nlm.nih.gov/pubmed/32671980
http://dx.doi.org/10.1002/cnr2.1231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941548/
https://www.ncbi.nlm.nih.gov/pubmed/32671980
http://dx.doi.org/10.1002/cnr2.1231

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