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Retinoic acid receptor γ is a therapeutically targetable driver of growth and survival in prostate cancer

BACKGROUND: Prostate cancer (PC) tissue contains all‐trans retinoic acid (ATRA) at a very low level (10(−9) M), at least an order of magnitude lower than in adjacent normal healthy prostate cells or benign prostate hyperplasia. When this is coupled with deregulated expression of the intracellular li...

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Detalles Bibliográficos
Autores principales: Petrie, Kevin, Urban‐Wójciuk, Zuzanna, Sbirkov, Yordan, Graham, Amy, Hamann, Annika, Brown, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941583/
https://www.ncbi.nlm.nih.gov/pubmed/32881426
http://dx.doi.org/10.1002/cnr2.1284