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CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors

BACKGROUND: Anti–programed cell death 1 checkpoint inhibitors have recently demonstrated effectiveness against metastatic cancers including urothelial carcinoma. AIMS: To identify biomarkers/factors that correlate with the clinical response in advanced bladder cancer patients who received immune che...

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Detalles Bibliográficos
Autores principales: Deng, Boya, Park, Jae‐Hyun, Ren, Lili, Yew, Poh Yin, Kiyotani, Kazuma, Antic, Tatjana, O'Connor, Kelly, O'Donnell, Peter H., Nakamura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941587/
https://www.ncbi.nlm.nih.gov/pubmed/32729250
http://dx.doi.org/10.1002/cnr2.1002