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DCAF14 promotes stalled fork stability to maintain genome integrity

Replication stress response ensures impediments to DNA replication do not compromise replication fork stability and genome integrity. In a process termed replication fork protection, newly synthesized DNA at stalled replication forks is stabilized and protected from nuclease-mediated degradation. We...

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Detalles Bibliográficos
Autores principales: Townsend, Arik, Lora, Gabriella, Engel, Justin, Tirado-Class, Neysha, Dungrawala, Huzefa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941590/
https://www.ncbi.nlm.nih.gov/pubmed/33503431
http://dx.doi.org/10.1016/j.celrep.2020.108669