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Persistent SARS-CoV-2 infection and increasing viral variants in children and young adults with impaired humoral immunity

BACKGROUND: There is increasing concern that persistent infection of SARS-CoV-2 within immunocompromised hosts could serve as a reservoir for mutation accumulation and subsequent emergence of novel strains with the potential to evade immune responses. METHODS: We describe three patients with acute l...

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Detalles Bibliográficos
Autores principales: Truong, Thao T., Ryutov, Alex, Pandey, Utsav, Yee, Rebecca, Goldberg, Lior, Bhojwani, Deepa, Aguayo-Hiraldo, Paibel, Pinsky, Benjamin A., Pekosz, Andrew, Shen, Lishuang, Boyd, Scott D., Wirz, Oliver F., Röltgen, Katharina, Bootwalla, Moiz, Maglinte, Dennis T., Ostrow, Dejerianne, Ruble, David, Han, Jennifer H., Biegel, Jaclyn A., Li, Maggie, Huang, ChunHong, Sahoo, Mayala K., Pannaraj, Pia S., O’Gorman, Maurice, Judkins, Alexander R., Gai, Xiaowu, Bard, Jennifer Dien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941650/
https://www.ncbi.nlm.nih.gov/pubmed/33688673
http://dx.doi.org/10.1101/2021.02.27.21252099