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The importance of CDC27 in cancer: molecular pathology and clinical aspects

BACKGROUND: CDC27 is one of the core components of Anaphase Promoting complex/cyclosome. The main role of this protein is defined at cellular division to control cell cycle transitions. Here we review the molecular aspects that may affect CDC27 regulation from cell cycle and mitosis to cancer pathog...

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Detalles Bibliográficos
Autores principales: Kazemi-Sefat, Golnaz Ensieh, Keramatipour, Mohammad, Talebi, Saeed, Kavousi, Kaveh, Sajed, Roya, Kazemi-Sefat, Nazanin Atieh, Mousavizadeh, Kazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941923/
https://www.ncbi.nlm.nih.gov/pubmed/33750395
http://dx.doi.org/10.1186/s12935-021-01860-9