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The ESCRT-III molecules regulate the apical targeting of bile salt export pump

BACKGROUND: The bile salt export pump (BSEP) is a pivotal apical/canalicular bile salt transporter in hepatocytes that drives the bile flow. Defects in BSEP function and canalicular expression could lead to a spectrum of cholestatic liver diseases. One prominent manifestation of BSEP-associated chol...

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Detalles Bibliográficos
Autores principales: Wu, Shang-Hsin, Chang, Mei-Hwei, Chen, Ya-Hui, Wu, Hui-Lin, Chua, Huey-Huey, Chien, Chin-Sung, Ni, Yen-Hsuan, Chen, Hui-Ling, Chen, Huey-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941988/
https://www.ncbi.nlm.nih.gov/pubmed/33750401
http://dx.doi.org/10.1186/s12929-020-00706-2