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MicroRNA-1182 and let-7a exert synergistic inhibition on invasion, migration and autophagy of cholangiocarcinoma cells through down-regulation of NUAK1

BACKGROUND: Cholangiocarcinoma (CCA) is the second most common primary liver malignancy worldwide. Several microRNAs (miRNAs) have been implicated as potential tumor suppressors in CCA. This study aims to explore the potential effects of miR-1182 and let-7a on CCA development. METHODS: Bioinformatic...

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Detalles Bibliográficos
Autores principales: Pan, Xin, Wang, Gang, Wang, Baoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942015/
https://www.ncbi.nlm.nih.gov/pubmed/33750398
http://dx.doi.org/10.1186/s12935-021-01797-z