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Genetic variation and microRNA targeting of A-to-I RNA editing fine tune human tissue transcriptomes

BACKGROUND: A-to-I RNA editing diversifies the transcriptome and has multiple downstream functional effects. Genetic variation contributes to RNA editing variability between individuals and has the potential to impact phenotypic variability. RESULTS: We analyze matched genetic and transcriptomic dat...

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Detalles Bibliográficos
Autores principales: Park, Eddie, Jiang, Yan, Hao, Lili, Hui, Jingyi, Xing, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942016/
https://www.ncbi.nlm.nih.gov/pubmed/33685485
http://dx.doi.org/10.1186/s13059-021-02287-1