Mutations of N1 Riboswitch Affect its Dynamics and Recognition by Neomycin Through Conformational Selection

Short, structured fragments of non-coding mRNA may act as molecular switches upon binding specific ligands, regulating the translation of proteins encoded downstream this mRNA sequence. One switch, called riboswitch N1, is regulated by aminoglycosides such as neomycin. Nucleobase mutations in the ap...

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Detalles Bibliográficos
Autores principales: Chyży, Piotr, Kulik, Marta, Re, Suyong, Sugita, Yuji, Trylska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942488/
https://www.ncbi.nlm.nih.gov/pubmed/33708793
http://dx.doi.org/10.3389/fmolb.2021.633130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942488/
https://www.ncbi.nlm.nih.gov/pubmed/33708793
http://dx.doi.org/10.3389/fmolb.2021.633130

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