AKT-dependent signaling of extracellular cues through telomeres impact on tumorigenesis

The telomere-bound shelterin complex is essential for chromosome-end protection and genomic stability. Little is known on the regulation of shelterin components by extracellular signals including developmental and environmental cues. Here, we show that human TRF1 is subjected to AKT-dependent regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Sánchez-Vázquez, Raúl, Martínez, Paula, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942993/
https://www.ncbi.nlm.nih.gov/pubmed/33690611
http://dx.doi.org/10.1371/journal.pgen.1009410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942993/
https://www.ncbi.nlm.nih.gov/pubmed/33690611
http://dx.doi.org/10.1371/journal.pgen.1009410

Ejemplares similares