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AKT-dependent signaling of extracellular cues through telomeres impact on tumorigenesis
The telomere-bound shelterin complex is essential for chromosome-end protection and genomic stability. Little is known on the regulation of shelterin components by extracellular signals including developmental and environmental cues. Here, we show that human TRF1 is subjected to AKT-dependent regula...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942993/ https://www.ncbi.nlm.nih.gov/pubmed/33690611 http://dx.doi.org/10.1371/journal.pgen.1009410 |