Linking bacterial enterotoxins and alpha defensin 5 expansion in the Crohn’s colitis: A new insight into the etiopathogenetic and differentiation triggers driving colonic inflammatory bowel disease

Evidence link bacterial enterotoxins to apparent crypt-cell like cells (CCLCs), and Alpha Defensin 5 (DEFA5) expansion in the colonic mucosa of Crohn’s colitis disease (CC) patients. These areas of ectopic ileal metaplasia, positive for Paneth cell (PC) markers are consistent with diagnosis of CC. R...

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Detalles Bibliográficos
Autores principales: Rana, Tanu, Korolkova, Olga Y., Rachakonda, Girish, Williams, Amanda D., Hawkins, Alexander T., James, Samuel D., Sakwe, Amos M., Hui, Nian, Wang, Li, Yu, Chang, Goodwin, Jeffrey S., Izban, Michael G., Offodile, Regina S., Washington, Mary K., Ballard, Billy R., Smoot, Duane T., Shi, Xuan-Zheng, Forbes, Digna S., Shanker, Anil, M’Koma, Amosy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942995/
https://www.ncbi.nlm.nih.gov/pubmed/33690604
http://dx.doi.org/10.1371/journal.pone.0246393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7942995/
https://www.ncbi.nlm.nih.gov/pubmed/33690604
http://dx.doi.org/10.1371/journal.pone.0246393

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