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Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding proteins

Peptidoglycan is an essential component of the bacterial cell envelope that surrounds the cytoplasmic membrane to protect the cell from osmotic lysis. Important antibiotics such as β-lactams and glycopeptides target peptidoglycan biosynthesis. Class A penicillin-binding proteins (PBPs) are bifunctio...

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Detalles Bibliográficos
Autores principales: Hernández-Rocamora, Víctor M, Baranova, Natalia, Peters, Katharina, Breukink, Eefjan, Loose, Martin, Vollmer, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943195/
https://www.ncbi.nlm.nih.gov/pubmed/33625355
http://dx.doi.org/10.7554/eLife.61525