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Polygenic Risk Scores Augment Stroke Subtyping

OBJECTIVE: To determine whether the polygenic risk score (PRS) derived from MEGASTROKE is associated with ischemic stroke (IS) and its subtypes in an independent tertiary health care system and to identify the PRS derived from gene sets of known biological pathways associated with IS. METHODS: Contr...

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Detalles Bibliográficos
Autores principales: Li, Jiang, Chaudhary, Durgesh P., Khan, Ayesha, Griessenauer, Christoph, Carey, David J., Zand, Ramin, Abedi, Vida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943221/
https://www.ncbi.nlm.nih.gov/pubmed/33709033
http://dx.doi.org/10.1212/NXG.0000000000000560