A Dual Target-Directed Single Domain-Based Fusion Protein Against Interleukin-6 Receptor Decelerate Experimental Arthritis Progression Via Modulating JNK Expression

The currently used anti-cytokine therapeutic antibodies cannot selectively neutralize pathogenic cytokine signalling that cause collateral damage to protective signalling cascades. The single domain chain firstly discovered in Camelidae displays fully functional ability in antigen-binding against va...

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Detalles Bibliográficos
Autores principales: Chen, Xiaole, Bian, Yize, Xie, Yongqing, Zheng, Ningning, Nie, Kaimei, Liu, Rui, Yan, Mengru, Luo, Hongbin, Wang, He, Yang, Juhua, Zhang, Nanwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943332/
https://www.ncbi.nlm.nih.gov/pubmed/33751358
http://dx.doi.org/10.1007/s10753-021-01446-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943332/
https://www.ncbi.nlm.nih.gov/pubmed/33751358
http://dx.doi.org/10.1007/s10753-021-01446-7

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