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Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E

Emetine is a FDA-approved drug for the treatment of amebiasis. Previously we demonstrated the antiviral efficacy of emetine against some RNA and DNA viruses. In this study, we evaluated the in vitro antiviral efficacy of emetine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) an...

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Detalles Bibliográficos
Autores principales: Kumar, Ram, Afsar, Mohammad, Khandelwal, Nitin, Chander, Yogesh, Riyesh, Thachamvally, Dedar, Ramesh Kumar, Gulati, Baldev R., Pal, Yash, Barua, Sanjay, Tripathi, Bhupendra N., Hussain, Tanweer, Kumar, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943376/
https://www.ncbi.nlm.nih.gov/pubmed/33711336
http://dx.doi.org/10.1016/j.antiviral.2021.105056