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Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E
Emetine is a FDA-approved drug for the treatment of amebiasis. Previously we demonstrated the antiviral efficacy of emetine against some RNA and DNA viruses. In this study, we evaluated the in vitro antiviral efficacy of emetine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) an...
Autores principales: | Kumar, Ram, Afsar, Mohammad, Khandelwal, Nitin, Chander, Yogesh, Riyesh, Thachamvally, Dedar, Ramesh Kumar, Gulati, Baldev R., Pal, Yash, Barua, Sanjay, Tripathi, Bhupendra N., Hussain, Tanweer, Kumar, Naveen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943376/ https://www.ncbi.nlm.nih.gov/pubmed/33711336 http://dx.doi.org/10.1016/j.antiviral.2021.105056 |
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