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Unsupervised Clustering Reveals Sarcoidosis Phenotypes Marked by a Reduction in Lymphocytes Relate to Increased Inflammatory Activity on 18FDG-PET/CT

Introduction: Sarcoidosis is a T-helper cell mediated disease characterized by granulomatous inflammation. We posited that unsupervised clustering of various features in sarcoidosis would establish phenotypes associated with inflammatory activity measured by 18FDG-PET/CT. Our goal was to identify un...

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Detalles Bibliográficos
Autores principales: Vagts, Christen, Ascoli, Christian, Fraidenburg, Dustin R., Baughman, Robert P., Huang, Yue, Edafetanure-Ibeh, Russell, Ahmed, Samreen, Levin, Benjamin, Lu, Yang, Perkins, David L., Finn, Patricia W., Sweiss, Nadera J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943443/
https://www.ncbi.nlm.nih.gov/pubmed/33718397
http://dx.doi.org/10.3389/fmed.2021.595077