Transcriptomic Profiling of In Vitro Tumor-Stromal Cell Paracrine Crosstalk Identifies Involvement of the Integrin Signaling Pathway in the Pathogenesis of Mesenteric Fibrosis in Human Small Intestinal Neuroendocrine Neoplasms

AIM: Analysis of the pathophysiology of mesenteric fibrosis (MF) in small intestinal neuroendocrine tumors (SI-NETs) in an in vitro paracrine model and in human SI-NET tissue samples. METHODS: An indirect co-culture model of SI-NET cells KRJ-I and P-STS with stromal cells HEK293 was designed to eval...

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Detalles Bibliográficos
Autores principales: Laskaratos, Faidon-Marios, Levi, Ana, Schwach, Gert, Pfragner, Roswitha, Hall, Andrew, Xia, Dong, von Stempel, Conrad, Bretherton, Josephine, Thanapirom, Kessarin, Alexander, Sarah, Ogunbiyi, Olagunju, Watkins, Jennifer, Luong, Tu Vinh, Toumpanakis, Christos, Mandair, Dalvinder, Caplin, Martyn, Rombouts, Krista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943728/
https://www.ncbi.nlm.nih.gov/pubmed/33718208
http://dx.doi.org/10.3389/fonc.2021.629665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943728/
https://www.ncbi.nlm.nih.gov/pubmed/33718208
http://dx.doi.org/10.3389/fonc.2021.629665

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