Eplerenone Attenuates Fibrosis in the Contralateral Kidney of UUO Rats by Preventing Macrophage-to-Myofibroblast Transition

Severe renal fibrosis often occurs in obstructive kidney disease, not only in the obstructed kidney but also in the contralateral kidney, causing renal dysfunction. Although the mechanisms of injury in obstructed kidney have been studied for years, the pathogenesis of fibrosis in the contralateral k...

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Detalles Bibliográficos
Autores principales: Xiong, Yunzhao, Chang, Yi, Hao, Juan, Zhang, Cuijuan, Yang, Fan, Wang, Zheng, Liu, Yunmeng, Wang, Xiangting, Mu, Shengyu, Xu, Qingyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943730/
https://www.ncbi.nlm.nih.gov/pubmed/33716747
http://dx.doi.org/10.3389/fphar.2021.620433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943730/
https://www.ncbi.nlm.nih.gov/pubmed/33716747
http://dx.doi.org/10.3389/fphar.2021.620433

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