Generation and characterization of CD19-iCre mice as a tool for efficient and specific conditional gene targeting in B cells

The Cre/loxP system is a powerful tool for generating conditional gene knockout (KO) mice and elucidate gene function in vivo. CD19-Cre and Mb1-iCre transgenic mice are commonly used for generating B cell-specific KO mice and investigate the development, as well as the physiological and pathophysiol...

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Detalles Bibliográficos
Autores principales: Yasuda, Tomoharu, Saito, Yuichi, Ono, Chisato, Kawata, Kazuhiko, Baba, Akemi, Baba, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943778/
https://www.ncbi.nlm.nih.gov/pubmed/33750849
http://dx.doi.org/10.1038/s41598-021-84786-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943778/
https://www.ncbi.nlm.nih.gov/pubmed/33750849
http://dx.doi.org/10.1038/s41598-021-84786-6

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