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Generation and characterization of CD19-iCre mice as a tool for efficient and specific conditional gene targeting in B cells
The Cre/loxP system is a powerful tool for generating conditional gene knockout (KO) mice and elucidate gene function in vivo. CD19-Cre and Mb1-iCre transgenic mice are commonly used for generating B cell-specific KO mice and investigate the development, as well as the physiological and pathophysiol...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943778/ https://www.ncbi.nlm.nih.gov/pubmed/33750849 http://dx.doi.org/10.1038/s41598-021-84786-6 |