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The less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization
Cysteine-rich secretory proteins (CRISPs) are a subgroup of the CRISP, antigen 5 and PR-1 (CAP) superfamily that is characterized by the presence of a conserved CAP domain. Two conserved histidines in the CAP domain are proposed to function as a Zn(2+)-binding site with unknown function. Human CRISP...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943821/ https://www.ncbi.nlm.nih.gov/pubmed/33750840 http://dx.doi.org/10.1038/s41598-021-84926-y |