The Deubiquitinating Enzyme UCHL1 Induces Resistance to Doxorubicin in HER2+ Breast Cancer by Promoting Free Fatty Acid Synthesis

Ubiquitin C-terminal hydrolase L1 (UCHL1), which is a deubiquitinating enzyme, is known to play a role in chemoresistance in cancers. However, its potential roles and mechanisms in the chemoresistance of breast cancer (BC) remain unclear. In this study, we examined its expression in patients with BC...

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Detalles Bibliográficos
Autores principales: Lu, Guangxian, Li, Jianhua, Ding, Leyun, Wang, Chenping, Tang, Lian, Liu, Xin, Xu, Jinhui, Zhou, Qin, Sun, Jiantong, Wang, Wenjuan, Ding, Xinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943833/
https://www.ncbi.nlm.nih.gov/pubmed/33718207
http://dx.doi.org/10.3389/fonc.2021.629640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943833/
https://www.ncbi.nlm.nih.gov/pubmed/33718207
http://dx.doi.org/10.3389/fonc.2021.629640

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