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TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC

Tumor necrosis factor-induced protein-8 (TIPE) is highly expressed in colorectal cancer (CRC). Decoy receptor 3 (DcR3) is a soluble secreted protein that can antagonize Fas ligand (FasL)-induced apoptosis and promote tumorigenesis. It remains unclear whether TIPE can regulate DcR3 expression. In thi...

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Detalles Bibliográficos
Autores principales: Zhong, Mengya, Qiu, Xingfeng, Liu, Yu, Yang, Yan, Gu, Lei, Wang, Chenxi, Chen, Huiyu, Liu, Zhongchen, Miao, Jiayin, Zhuang, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943851/
https://www.ncbi.nlm.nih.gov/pubmed/33718119
http://dx.doi.org/10.3389/fonc.2020.623048