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The NTCP p.Ser267Phe Variant Is Associated With a Faster Anti-HBV Effect on First-Line Nucleos(t)ide Analog Treatment

Sodium taurocholate cotransporting polypeptide (NTCP) acts as a cellular receptor for the hepatitis B virus infection of host hepatocytes. Previously, many studies confirmed that the NTCP p.Ser267Phe variant was a protective factor against HBV-related disease progression. We therefore designed this...

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Detalles Bibliográficos
Autores principales: Wu, Lina, Xu, Wenxiong, Li, Xuejun, Liu, Ying, Wang, Lu, Zhu, Shu, Yang, Fangji, Xie, Chan, Peng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7943921/
https://www.ncbi.nlm.nih.gov/pubmed/33716744
http://dx.doi.org/10.3389/fphar.2021.616858