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Taurine rescues mitochondria-related metabolic impairments in the patient-derived induced pluripotent stem cells and epithelial-mesenchymal transition in the retinal pigment epithelium

Mitochondria participate in various metabolic pathways, and their dysregulation results in multiple disorders, including aging-related diseases. However, the metabolic changes and mechanisms of mitochondrial disorders are not fully understood. Here, we found that induced pluripotent stem cells (iPSC...

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Detalles Bibliográficos
Autores principales: Homma, Kohei, Toda, Eriko, Osada, Hideto, Nagai, Norihiro, Era, Takumi, Tsubota, Kazuo, Okano, Hideyuki, Ozawa, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944050/
https://www.ncbi.nlm.nih.gov/pubmed/33706170
http://dx.doi.org/10.1016/j.redox.2021.101921