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Metformin Protects Myelin from Degeneration in A Mouse Model of Iysophosphatidylcholine-Induced Demyelination in The Optic Chiasm

OBJECTIVE: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. The autoimmune pathology and long-term inflammation lead to substantial demyelination. These events lead to a substantial loss of oligodendrocytes (OLs), which in a longer period, results in axonal loss and...

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Detalles Bibliográficos
Autores principales: Esmaeilnejad, Saman, Semnanian, Saeed, Javan, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944130/
https://www.ncbi.nlm.nih.gov/pubmed/33650828
http://dx.doi.org/10.22074/cellj.2021.7174