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Impact of Methyl-β-Cyclodextrin and Apolipoprotein A-I on The Expression of ATP-Binding Cassette Transporter A1 and Cholesterol Depletion in C57BL/6 Mice Astrocytes

OBJECTIVE: Dysregulation of cholesterol metabolism in the brain is responsible for many lipid storage disorders, including Niemann-Pick disease type C (NPC). Here, we have investigated whether cyclodextrin (CD) and apolipoprotein A-I (apoA-I) induce the same signal to inhibit cell cholesterol accumu...

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Detalles Bibliográficos
Autores principales: Azizidoost, Shirin, Babaahmadi-Rezaei, Hossein, Nazeri, Zahra, Cheraghzadeh, Maryam, Kheirollah, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944131/
https://www.ncbi.nlm.nih.gov/pubmed/33650825
http://dx.doi.org/10.22074/cellj.2021.7061