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Rationale and Application of PEGylated Lipid-Based System for Advanced Target Delivery of siRNA

RNA interference (RNAi) technology has become a powerful tool in application of unraveling the mechanism of disease and may hold the potential to be developed for clinical uses. Small interfering RNA (siRNA) can bind to target mRNA with high specificity and efficacy and thus inhibit the expression o...

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Detalles Bibliográficos
Autores principales: Ge, Xuemei, Chen, Lijuan, Zhao, Bo, Yuan, Weien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944141/
https://www.ncbi.nlm.nih.gov/pubmed/33716725
http://dx.doi.org/10.3389/fphar.2020.598175