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SOX2 amplification and chromosome 3 gain significantly impact prognosis in esophageal squamous cell carcinoma

BACKGROUND: We aimed to investigate the prevalence and prognostic role of Sex determining region Y-box 2 (SOX2) amplification and expression in surgically resected esophageal squamous cell carcinoma (ESCC). METHODS: We evaluated 450 ESCC samples using fluorescence in-situ hybridization and immunohis...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Ge, Xiaowen, Wang, Haixing, Huang, Jie, Song, Qi, Xu, Chen, Jiang, Zhengzeng, Su, Jieakesu, Wang, Hao, Tan, Lijie, Jiang, Dongxian, Hou, Yingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944334/
https://www.ncbi.nlm.nih.gov/pubmed/33708948
http://dx.doi.org/10.21037/atm-20-1290