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Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma

BACKGROUND: Glaucoma is a neurodegenerative disease that shares similar pathological mechanisms with Alzheimer’s disease (AD). Drug treatments for glaucoma increasingly rely upon both lowering of intraocular pressure (IOP) and optic nerve protection, as lowering of IOP alone has been unsatisfactory....

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Detalles Bibliográficos
Autores principales: Yu, Ping, Dong, Wen-Pei, Tang, Ya-Bin, Chen, Hong-Zhuan, Cui, Yong-Yao, Bian, Xiao-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944337/
https://www.ncbi.nlm.nih.gov/pubmed/33708959
http://dx.doi.org/10.21037/atm-20-8093