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Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma
BACKGROUND: Glaucoma is a neurodegenerative disease that shares similar pathological mechanisms with Alzheimer’s disease (AD). Drug treatments for glaucoma increasingly rely upon both lowering of intraocular pressure (IOP) and optic nerve protection, as lowering of IOP alone has been unsatisfactory....
Autores principales: | Yu, Ping, Dong, Wen-Pei, Tang, Ya-Bin, Chen, Hong-Zhuan, Cui, Yong-Yao, Bian, Xiao-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944337/ https://www.ncbi.nlm.nih.gov/pubmed/33708959 http://dx.doi.org/10.21037/atm-20-8093 |
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