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Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Shaker potassium channel

Voltage-gated potassium (K(V)) channels can be opened by negatively charged resin acids and their derivatives. These resin acids have been proposed to attract the positively charged voltage-sensor helix (S4) toward the extracellular side of the membrane by binding to a pocket located between the lip...

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Detalles Bibliográficos
Autores principales:	Silverå Ejneby, Malin, Gromova, Arina, Ottosson, Nina E., Borg, Stina, Estrada-Mondragón, Argel, Yazdi, Samira, Apostolakis, Panagiotis, Elinder, Fredrik, Delemotte, Lucie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7944402/ https://www.ncbi.nlm.nih.gov/pubmed/33683319 http://dx.doi.org/10.1085/jgp.202012676

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